Born in Freiburg / Germany, Sophie Klussmann studied at the music conservatories of Detmold with Thomas Quasthoff and Köln with Klesie Kelly-Moog. Awards include the Mozart Competition Würzburg and the Trude Eiperle Stiftung.
She is a versatile concert, opera and recital singer, who is internationally in demand. Her work with conductors such as Vladimir Jurowski, Helmuth Rilling, Ingo Metzmacher, Marek Janowski, Christoph Eschenbach and Marcus Bosch has taken her to some of the most distinguished orchestras of Europe, including both Radio Orchestras of Berlin, the Konzerthaus Orchestra Berlin, SWR Orchestra, Staatsphilharmonie Nürnberg, Orchestre de chambre de Paris, Tonhalle Orchestra Zürich and the Wiener Akademie. In 2024 she debuted at Shanghai Concert Hall with the production „Silent Songs“ by Nico and the Navigators.

Early in her career, she was member of the opera Halle, singing the leading lyric soprano parts. In 2021/22 she sang the leading role of „The merry widow“ by Franz Léhar at the State Theatre of Cottbus.
With the Akademie für alte Musik/Marcus Creed, Collegium 1704/Václav Luks and the Orchestra of the Eighteenth Century/Daniel Reuß, she worked intensively in the field of ancient music. Together with Lutinist Hopkinson Smith, Sophie Klussmann created as renaissance program, which they perform at different international festivals such as Lübeck and Weimar, Germany, Montserat. In 2025, under the french label naive, the album „Chansons&Frottole“ will be published.

Sophie performed and recorded a number of contemporary pieces by composers such as György Kurtág, György Ligeti and Karl-Heinz Stockhausen at venues as MaerzMusikFestival Berlin and Milano Musica. Composers such as Christian Jost and Xavier Dayer wrote pieces for her. Some of them she recorded at the Swiss Radio together with the american pianist Gilles Vonsattel and the violist and director of the Swiss Chamber Soloists Jürg Dähler. In 2026, her recording of „The sayings by Peter Bornemisza“ by Kurtag will be published unter the label Odradek.
Her passionate love for chamber music and Lied repertoire brings her frequently to chamber music venues such as Kuhmo Chamber Music Festival, Kempten Festival and the Stift Festival Holland. Sophies’s artistic activity is documented on many recordings including, among others, Dixit Dominus/ Händel under Marcus Creed (Harmonia Mundi), first recording of songs by Zemlinsky-student Karl Weigl with Oliver Triendl, piano (Capriccio) and song cycles by Stefano Gervasoni (Cini Forum Venezia). In 2023 her recording of the Japanese Songs by Grete von Zieritz at Hänssler Classics were very well received.

Since 2023, Sophie Klussmann has a lectureship for classical singing at the University of Arts Berlin.